The urine/plasma electrolyte ratio: a predictive guide to water restriction

Am J Med Sci. 2000 Apr;319(4):240-4. doi: 10.1097/00000441-200004000-00007.

Abstract

Patients with hypotonic hyponatremia are encountered commonly in the general practice of medicine. Nearly all strategies for the management of subacute or chronic hyponatremia call for some amount of water restriction. The considerations for such a prescription have not been addressed in the literature. We describe therefore a simple approach grounded in the physiology of electrolyte-free water clearance that can be used at the bedside.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Electrolytes / blood*
  • Electrolytes / urine*
  • Humans
  • Hyponatremia / blood
  • Hyponatremia / complications
  • Hyponatremia / metabolism*
  • Hyponatremia / therapy*
  • Hyponatremia / urine
  • Predictive Value of Tests
  • Water / administration & dosage*
  • Water Intoxication / blood
  • Water Intoxication / etiology
  • Water Intoxication / metabolism*
  • Water Intoxication / prevention & control*
  • Water Intoxication / urine

Substances

  • Electrolytes
  • Water