Abstract
Transcriptional regulation and membrane traffic have traditionally been quite separate fields of biology, but they have been brought under the same roof by recent advances in understanding the cellular control of cholesterol metabolism.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Animals
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CCAAT-Enhancer-Binding Proteins*
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Cholesterol / metabolism*
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DNA-Binding Proteins / metabolism*
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Endoplasmic Reticulum / drug effects
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Endoplasmic Reticulum / metabolism*
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Golgi Apparatus / metabolism
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Humans
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Intracellular Signaling Peptides and Proteins
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Membrane Proteins / metabolism
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Nuclear Proteins / metabolism*
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Proprotein Convertases*
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Serine Endopeptidases / pharmacology
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Sterol Regulatory Element Binding Protein 1
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Transcription Factors / metabolism
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Transcription, Genetic
Substances
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CCAAT-Enhancer-Binding Proteins
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DNA-Binding Proteins
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Intracellular Signaling Peptides and Proteins
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Membrane Proteins
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Nuclear Proteins
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SREBF1 protein, human
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SREBP cleavage-activating protein
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Sterol Regulatory Element Binding Protein 1
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Transcription Factors
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Cholesterol
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Proprotein Convertases
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Serine Endopeptidases
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membrane-bound transcription factor peptidase, site 1