Sortase, a universal target for therapeutic agents against gram-positive bacteria?

Proc Natl Acad Sci U S A. 2000 May 9;97(10):5013-5. doi: 10.1073/pnas.97.10.5013.
No abstract available

Publication types

  • Comment
  • Review

MeSH terms

  • Amino Acid Sequence
  • Aminoacyltransferases / metabolism*
  • Animals
  • Bacterial Proteins
  • Cell Wall / physiology
  • Cysteine Endopeptidases
  • Gram-Positive Bacteria / enzymology
  • Gram-Positive Bacteria / pathogenicity*
  • Gram-Positive Bacterial Infections / microbiology*
  • Humans
  • Peptidoglycan / biosynthesis
  • Peptidoglycan / chemistry
  • Staphylococcal Infections / microbiology
  • Staphylococcus aureus / enzymology
  • Staphylococcus aureus / pathogenicity*
  • Virulence

Substances

  • Bacterial Proteins
  • Peptidoglycan
  • Aminoacyltransferases
  • sortase A
  • Cysteine Endopeptidases