Abstract
In rats with experimental acute pancreatitis, activity of the antioxidant defense enzyme in pancreatic and liver tissues increases, while that in the blood erythrocytes decreases. Preliminary administration of SH-compounds, especially unithiol, favored an increase in the activity of superoxide dismutase, catalase, and glutathione peroxidaze.
MeSH terms
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Acute Disease
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Animals
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Catalase / blood
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Catalase / metabolism*
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Cysteine / pharmacology
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Glutathione Peroxidase / blood
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Glutathione Peroxidase / metabolism*
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Liver / enzymology
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Male
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Methionine / pharmacology
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Pancreas / enzymology
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Pancreatitis / enzymology*
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Rats
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Sulfhydryl Compounds / pharmacology*
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Superoxide Dismutase / blood
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Superoxide Dismutase / metabolism*
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Unithiol / pharmacology
Substances
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Sulfhydryl Compounds
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Unithiol
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Methionine
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Catalase
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Glutathione Peroxidase
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Superoxide Dismutase
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Cysteine