Comparison of quinapril versus atenolol: effects on blood pressure and cardiac mass after renal transplantation

Am J Cardiol. 2000 Sep 1;86(5):583-5, A10. doi: 10.1016/s0002-9149(00)01024-9.

Abstract

Based on epidemiologic facts on elevated cardiovascular mortality in renal allograft recipients, an echocardiographic 2-year follow-up in hypertensive renal allograft recipients was conducted. This study provides evidence that, in contrast to atenolol, quinapril, independent of blood pressure reduction, reduces left ventricular hypertrophy and improves left ventricular diastolic function in this population.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adrenergic beta-Antagonists / pharmacology*
  • Adrenergic beta-Antagonists / therapeutic use
  • Angiotensin-Converting Enzyme Inhibitors / pharmacology*
  • Angiotensin-Converting Enzyme Inhibitors / therapeutic use
  • Antihypertensive Agents / pharmacology
  • Antihypertensive Agents / therapeutic use
  • Atenolol / pharmacology*
  • Atenolol / therapeutic use
  • Blood Pressure / drug effects*
  • Diastole / drug effects
  • Double-Blind Method
  • Heart Ventricles / anatomy & histology
  • Heart Ventricles / drug effects
  • Humans
  • Hypertension / drug therapy
  • Hypertension / physiopathology*
  • Hypertrophy, Left Ventricular / drug therapy*
  • Isoquinolines / pharmacology*
  • Isoquinolines / therapeutic use
  • Kidney Transplantation / physiology*
  • Middle Aged
  • Quinapril
  • Tetrahydroisoquinolines*
  • Ventricular Function

Substances

  • Adrenergic beta-Antagonists
  • Angiotensin-Converting Enzyme Inhibitors
  • Antihypertensive Agents
  • Isoquinolines
  • Tetrahydroisoquinolines
  • Atenolol
  • Quinapril