Presentation of MHC-disparate donor antigens predominantly by the indirect pathway results in the development of posttransplant vasculopathy: salutary effects of perioperative costimulatory blockade

Transplant Proc. 2001 Feb-Mar;33(1-2):307. doi: 10.1016/s0041-1345(00)02020-0.

Authors

J L Tang¹, J E Woodward, V Subbotin, A J Logar, H Sun, L A Valdivia, A T Schaefer, L B Zottola, R Peach, J J Fung, A S Rao

Affiliation

¹ Section of Cellular Transplantation, Thomas E. Starzl Transplantation Institute, Pittsburgh, Pennsylvania, USA.

PMID: 11266831
DOI: 10.1016/s0041-1345(00)02020-0

No abstract available

MeSH terms

Animals
Antigen Presentation / immunology*
Aorta, Thoracic / pathology
Aorta, Thoracic / transplantation*
B7-1 Antigen / drug effects
B7-1 Antigen / immunology
CD28 Antigens / drug effects
CD28 Antigens / immunology
CD40 Antigens / drug effects
CD40 Antigens / immunology
CD40 Ligand / drug effects
CD40 Ligand / immunology
Histocompatibility Antigens / immunology*
Mice
Mice, Inbred C3H
Mice, Inbred C57BL
Tunica Intima / pathology*

Substances

B7-1 Antigen
CD28 Antigens
CD40 Antigens
Histocompatibility Antigens
CD40 Ligand