Optic neuropathy and central retinal vascular obstruction as initial manifestations of acute retinal necrosis

Jpn J Ophthalmol. 2001 Jul-Aug;45(4):425-8. doi: 10.1016/s0021-5155(01)00336-7.

Abstract

Background: The purpose of this brief communication is to alert ophthalmologists that optic neuropathy may herald acute retinal necrosis (ARN).

Case: A previously healthy 54-year-old man exhibited optic neuropathy as an initial presentation of ARN, 8 weeks after varicella-zoster dermatitis.

Observations: Central retinal vascular obstruction developed subsequently in his left eye. Later, the classic presentation of ARN appeared in his contralateral eye. Systemic acyclovir therapy stopped the progression of retinitis and resulted in healing of retinal lesions in his right eye.

Conclusions: This case suggests that optic neuropathy, especially with preceding herpetic dermatitis, should be suspected as the prodrome of ARN.

Publication types

  • Case Reports

MeSH terms

  • Acyclovir / therapeutic use
  • Antiviral Agents / therapeutic use
  • Dermatitis / diagnosis
  • Dermatitis / drug therapy
  • Dermatitis / virology
  • Herpes Zoster / diagnosis
  • Herpes Zoster / drug therapy
  • Humans
  • Male
  • Middle Aged
  • Optic Nerve Diseases / diagnosis*
  • Optic Nerve Diseases / drug therapy
  • Optic Nerve Diseases / virology
  • Retinal Artery Occlusion / diagnosis*
  • Retinal Artery Occlusion / drug therapy
  • Retinal Artery Occlusion / virology
  • Retinal Necrosis Syndrome, Acute / diagnosis*
  • Retinal Necrosis Syndrome, Acute / drug therapy
  • Retinal Necrosis Syndrome, Acute / virology
  • Retinal Vein Occlusion / diagnosis*
  • Retinal Vein Occlusion / drug therapy
  • Retinal Vein Occlusion / virology

Substances

  • Antiviral Agents
  • Acyclovir