Molecular architecture of adherens junctions

Curr Opin Cell Biol. 2001 Oct;13(5):600-3. doi: 10.1016/s0955-0674(00)00257-x.

Abstract

Adherens junctions are composed of a cadherin-catenin complex and its associated proteins. Recently, an increasing number of novel members of adherens junctions, including membrane and PDZ proteins, have been reported. Interactions among these components in adherens junctions seem to be dynamically regulated during the formation of adherens junction complexes in epithelial cells.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adherens Junctions / chemistry*
  • Adherens Junctions / physiology
  • Animals
  • Caenorhabditis elegans Proteins*
  • Cytoskeletal Proteins / metabolism
  • Epithelial Cells / metabolism
  • Helminth Proteins / metabolism
  • Membrane Proteins / analysis
  • Membrane Proteins / metabolism
  • Models, Biological
  • Muscle Proteins / metabolism
  • Phosphoproteins / analysis
  • Signal Transduction
  • Zonula Occludens-1 Protein
  • alpha Catenin

Substances

  • Caenorhabditis elegans Proteins
  • Cytoskeletal Proteins
  • Helminth Proteins
  • LIN-7 protein, C elegans
  • Membrane Proteins
  • Muscle Proteins
  • Phosphoproteins
  • Zonula Occludens-1 Protein
  • alpha Catenin