Regulation of arachidonate metabolism via lipoxygenase and cyclo-oxygenase by 12-HPETE, the product of human platelet lipoxygenase

Biochem Biophys Res Commun. 1979 Aug 28;89(4):1273-80. doi: 10.1016/0006-291x(79)92146-6.
No abstract available

MeSH terms

  • Arachidonic Acids / blood*
  • Blood Platelets / enzymology*
  • Collagen / pharmacology
  • Humans
  • Indomethacin / pharmacology
  • Kinetics
  • Leukotrienes
  • Lipoxygenase / blood*
  • Peroxides / blood
  • Platelet Aggregation / drug effects
  • Prostaglandin-Endoperoxide Synthases / metabolism*
  • Structure-Activity Relationship

Substances

  • Arachidonic Acids
  • Leukotrienes
  • Peroxides
  • 12-HPETE
  • Collagen
  • Lipoxygenase
  • Prostaglandin-Endoperoxide Synthases
  • Indomethacin