Cell polarity: following formin function

Curr Biol. 2002 Jan 8;12(1):R6-8. doi: 10.1016/s0960-9822(01)00637-6.

Abstract

Mutation of a novel fission yeast formin, for3p, leads to marked changes in both the actin and microtubule cytoskeleton, as well as a surprising asymmetric pattern of cell growth. At the same time, new work in budding yeast implicates formins directly in actin filament assembly.

Publication types

  • Comment

MeSH terms

  • Actin Cytoskeleton / ultrastructure
  • Actins / metabolism
  • Cell Cycle Proteins*
  • Cell Division
  • Cell Polarity*
  • Formins
  • Microtubules / ultrastructure
  • Models, Biological*
  • Mutation
  • Protein Structure, Tertiary
  • Schizosaccharomyces / growth & development*
  • Schizosaccharomyces / ultrastructure
  • Schizosaccharomyces pombe Proteins / chemistry
  • Schizosaccharomyces pombe Proteins / genetics
  • Schizosaccharomyces pombe Proteins / physiology*

Substances

  • Actins
  • Cell Cycle Proteins
  • FOR3 protein, S pombe
  • Formins
  • Schizosaccharomyces pombe Proteins