Abstract
Mutation of a novel fission yeast formin, for3p, leads to marked changes in both the actin and microtubule cytoskeleton, as well as a surprising asymmetric pattern of cell growth. At the same time, new work in budding yeast implicates formins directly in actin filament assembly.
MeSH terms
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Actin Cytoskeleton / ultrastructure
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Actins / metabolism
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Cell Cycle Proteins*
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Cell Division
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Cell Polarity*
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Formins
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Microtubules / ultrastructure
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Models, Biological*
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Mutation
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Protein Structure, Tertiary
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Schizosaccharomyces / growth & development*
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Schizosaccharomyces / ultrastructure
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Schizosaccharomyces pombe Proteins / chemistry
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Schizosaccharomyces pombe Proteins / genetics
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Schizosaccharomyces pombe Proteins / physiology*
Substances
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Actins
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Cell Cycle Proteins
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FOR3 protein, S pombe
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Formins
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Schizosaccharomyces pombe Proteins