The therapeutic potential of modulating the ceramide/sphingomyelin pathway

J Clin Invest. 2002 Jul;110(1):3-8. doi: 10.1172/JCI16127.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Amidohydrolases / metabolism
  • Angioplasty, Balloon, Coronary
  • Animals
  • Apoptosis / physiology
  • Biophysical Phenomena
  • Biophysics
  • Ceramidases
  • Ceramides / chemistry
  • Ceramides / metabolism*
  • Coronary Artery Disease / drug therapy
  • Coronary Artery Disease / therapy
  • Coronary Restenosis / prevention & control
  • Humans
  • Models, Biological
  • Neoplasms / drug therapy
  • Oxidoreductases / metabolism
  • Second Messenger Systems
  • Signal Transduction
  • Sphingomyelin Phosphodiesterase / metabolism
  • Sphingomyelins / chemistry
  • Sphingomyelins / metabolism*
  • Transferases (Other Substituted Phosphate Groups) / metabolism

Substances

  • Ceramides
  • Sphingomyelins
  • Oxidoreductases
  • dihydroceramide desaturase
  • Transferases (Other Substituted Phosphate Groups)
  • phosphatidylcholine-ceramide phosphocholine transferase
  • Sphingomyelin Phosphodiesterase
  • Amidohydrolases
  • Ceramidases