The chemistry and biology of the bryostatin antitumour macrolides

Nat Prod Rep. 2002 Aug;19(4):413-53. doi: 10.1039/b009211h.

Abstract

This review summarises the main developments that have occurred in bryostatin chemistry over the period 1982 to 2001 and has 117 references.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Antineoplastic Agents*
  • Bryostatins
  • Catalysis
  • Cyclization
  • Humans
  • Lactones / chemical synthesis*
  • Lactones / chemistry*
  • Macrolides*
  • Models, Molecular
  • Molecular Structure
  • Stereoisomerism

Substances

  • Antineoplastic Agents
  • Bryostatins
  • Lactones
  • Macrolides
  • bryostatin 1