Adult Henoch-Schönlein purpura with glomerulonephritis and paroxysmal nocturnal haemoglobinuria: an uncommon association

Clin Rheumatol. 2002 Sep;21(5):408-10. doi: 10.1007/s100670200109.

Abstract

Henoch-Schönlein purpura (HSP) is considered to be a small blood vessel systemic vasculitis. Numerous microorganisms have been implicated in triggering HSP. We describe an unusual case of HSP with glomerulonephritis and renal failure requiring haemodialysis in a young adult man who subsequently developed paroxysmal nocturnal haemoglobinuria (PNH) with several haemolytic episodes. Bacterial infections, especially those of the respiratory and urinary tract, might trigger both the diseases.

Publication types

  • Case Reports

MeSH terms

  • Acute Kidney Injury / complications
  • Acute Kidney Injury / diagnosis*
  • Acute Kidney Injury / therapy
  • Adult
  • Combined Modality Therapy
  • Drug Therapy, Combination
  • Erythrocyte Transfusion
  • Follow-Up Studies
  • Glomerulonephritis / complications
  • Glomerulonephritis / diagnosis*
  • Glomerulonephritis / therapy
  • Hemoglobinuria, Paroxysmal / complications
  • Hemoglobinuria, Paroxysmal / diagnosis*
  • Hemoglobinuria, Paroxysmal / therapy
  • Humans
  • IgA Vasculitis / complications
  • IgA Vasculitis / diagnosis*
  • IgA Vasculitis / therapy
  • Male
  • Renal Dialysis
  • Risk Assessment
  • Treatment Outcome