Abstract
Cloning by nuclear transfer from adult somatic cells is a remarkable demonstration of developmental plasticity. When a nucleus is placed in oocyte cytoplasm, the changes in chromatin structure that govern differentiation can be reversed, and the nucleus can be made to control development to term.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Cattle
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Cell Cycle
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Cell Differentiation
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Cloning, Organism*
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Embryonic and Fetal Development
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Fetal Death
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Forecasting
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Gene Expression Regulation, Developmental
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Goats
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Mice
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Nuclear Transfer Techniques*
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Oocytes / cytology
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Ploidies
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Sheep
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Swine