Generation of recombinant immunotoxins for specific targeting of tumor-related peptides presented by MHC molecules

Methods Mol Biol. 2003:207:269-82. doi: 10.1385/1-59259-334-8:269.

Authors

Cyril J Cohen¹, Galit Denkberg, Dina Segal, Yoram Reiter

Affiliation

¹ Faculty of Biology, Technion-Israel Institute of Technology, Haifa, Israel.

PMID: 12412480
DOI: 10.1385/1-59259-334-8:269

No abstract available

MeSH terms

Antigen Presentation
Genetic Engineering / methods*
Histocompatibility Antigens Class I / chemistry
Histocompatibility Antigens Class I / genetics
Histocompatibility Antigens Class I / immunology*
Humans
Immunoglobulin Variable Region / chemistry
Immunoglobulin Variable Region / genetics
Immunoglobulin Variable Region / immunology
Immunotherapy / methods*
Immunotoxins / adverse effects
Immunotoxins / isolation & purification*
Immunotoxins / therapeutic use*
Mutagenesis
Neoplasms / immunology
Neoplasms / therapy*
Peptide Fragments / immunology*
Recombinant Proteins / therapeutic use*

Substances

Histocompatibility Antigens Class I
Immunoglobulin Variable Region
Immunotoxins
Peptide Fragments
Recombinant Proteins