Increased disk size in glaucomatous eyes vs normal eyes in the Reykjavik eye study

Am J Ophthalmol. 2003 Feb;135(2):226-8. doi: 10.1016/s0002-9394(02)01928-1.

Abstract

Purpose: To evaluate the use of disk diameter as an indicator in the identification of glaucomatous optic neuropathy.

Methods: We evaluated all available stereofundus photographs for 1,040 right eyes obtained in the Reykjavik Eye Study. Horizontal and vertical disk diameters were determined in a masked manner by a glaucoma specialist (K.F.D.). All disk diameters were corrected for refractive error.

Results: There were significant differences (P <.05) between the corrected vertical disk diameters of normal subjects (0.189 +/- 0.018 inches) and those suspected of having glaucoma (0.202 +/- 0.020 inches) as well as between the normal and the glaucoma groups (0.206 +/- 0.029 inches). The corrected horizontal measurement showed the same pattern.

Conclusions: In the Reykjavik Eye Study, optic disks meeting structural criteria for glaucoma are significantly larger than normal nerves.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Glaucoma, Open-Angle / diagnosis*
  • Humans
  • Iceland
  • Middle Aged
  • Ocular Hypertension / diagnosis
  • Optic Disk / pathology*
  • Optic Nerve Diseases / diagnosis*
  • Photography
  • ROC Curve