Methadone induced mortality as a function of the circadian cycle

Nature. 1972 Oct 13;239(5372):397-8. doi: 10.1038/239397a0.

Authors

R H Lenox¹, T W Frazier

Affiliation

¹ Department of Psychiatry and Neurology, Walter Reed General Hospital, Washington, DC 20012, USA.

PMID: 12635301
DOI: 10.1038/239397a0

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Circadian Rhythm / physiology*
Darkness
Drug Overdose*
Heroin Dependence / rehabilitation
Lethal Dose 50
Light
Methadone / administration & dosage*
Methadone / adverse effects
Methadone / toxicity*
Rats
Survival Rate

Substances

Methadone