Ultrahigh-resolution optical coherence tomography by broadband continuum generation from a photonic crystal fiber

Opt Lett. 2003 Feb 1;28(3):182-4. doi: 10.1364/ol.28.000182.

Abstract

We have developed an ultrahigh-resolution optical coherence tomographic system in which broadband continuum generation from a photonic crystal fiber is used to produce high longitudinal resolution. Longitudinal resolution of 1.3-microm has been achieved in a biological tissue by use of continuum light from 800 to 1400 nm. The system employed a dynamic-focusing tracking method to maintain high lateral resolution over a large imaging depth. Subcellular imaging is demonstrated.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Equipment Design
  • Feasibility Studies
  • Larva / cytology
  • Models, Theoretical
  • Tomography, Optical Coherence* / instrumentation*
  • Tomography, Optical Coherence* / methods*
  • Xenopus / growth & development