Abstract
Glucagon effectively prevented the increase in glucose-6-phosphate dehodrogenase activity of rat liver following the administration of a glucose-casein mixture without altering the amount of the diet consumed. However, the increase of the enzyme level in carbon tetrachloride-injured rat liver was virtually insensitive to glucagon. The results obtained gave further evidence for the difference between these two induction mechanisms of glucose-6-phosphate dehydrogenase.
MeSH terms
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Animals
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Carbon Tetrachloride Poisoning / enzymology
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Diet
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Enzyme Induction / drug effects
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Glucagon / pharmacology*
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Glucokinase / metabolism
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Glucosephosphate Dehydrogenase / biosynthesis*
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Hexokinase / metabolism
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Isoenzymes / metabolism
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Liver / drug effects
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Liver / enzymology*
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Liver Glycogen / metabolism
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Male
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Pyruvate Kinase / metabolism
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Rats
Substances
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Isoenzymes
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Liver Glycogen
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Glucagon
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Glucosephosphate Dehydrogenase
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Hexokinase
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Glucokinase
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Pyruvate Kinase