Risk factors for the bipolar and depression spectra

Acta Psychiatr Scand Suppl. 2003:(418):15-9. doi: 10.1034/j.1600-0447.108.s418.4.x.

Abstract

Objective: To identify risk factors for mood disorders in a community sample studied from the ages of 20 to 35 years.

Method: Social characteristics, a family history of mood disorders and some personality features were analysed as risk factors for bipolar and depressive disorders by means of logistic regression.

Results: Frequent 'ups and downs' of mood were the strongest risk factor for both bipolar and depressive disorders; a weaker risk factor for both was emotional/vegetative lability (neuroticism). An additional risk factor for bipolar disorders was a positive family history of mania, whereas for depression it was a positive family history of depression/fatigue. As a risk factor for bipolar disorders, 'ups and downs' were much stronger than a positive family history of mania. Frequent ups and downs were independent of the family history of mood disorders.

Conclusion: The results suggest that mood regulation should be investigated as a new, very important independent risk factor for mood disorders.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Affect*
  • Bipolar Disorder / etiology*
  • Bipolar Disorder / psychology
  • Depressive Disorder / etiology*
  • Depressive Disorder / psychology
  • Family Relations
  • Fatigue
  • Female
  • Humans
  • Male
  • Regression Analysis
  • Risk Factors