Abstract
The immunostimulation effect of the selected Propionibacterium acnes strain 16073 was described. The optimal conditions for the preparation of the P. acnes vaccine and the nonspecific immunostimulation effects of the vaccine on various experimental infections were evaluated.
MeSH terms
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Adjuvants, Immunologic / pharmacology*
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Animals
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Bacterial Vaccines / pharmacology*
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Female
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Gram-Positive Bacterial Infections / immunology*
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Gram-Positive Bacterial Infections / pathology
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Liver / pathology
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Lymph Nodes / pathology
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Mice
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Mice, Inbred ICR
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Propionibacterium acnes / immunology*
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Spleen / pathology
Substances
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Adjuvants, Immunologic
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Bacterial Vaccines