Abstract
CHRD (after SWISSPROT abbreviation for chordin) is a novel domain identified in chordin, an inhibitor of bone morphogenetic proteins. Database searches have revealed several microbial homologues to this domain. It is anticipated to have an immunoglobulin-like beta-barrel structure based on limited similarity to superoxide dismutases but, as yet, no clear functional prediction can be made.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Amino Acid Sequence
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Bacterial Proteins / chemistry*
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Bacterial Proteins / genetics*
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Bone Morphogenetic Proteins / antagonists & inhibitors
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Glycoproteins / chemistry*
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Glycoproteins / genetics*
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Glycoproteins / pharmacology
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Intercellular Signaling Peptides and Proteins*
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Molecular Sequence Data
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Protein Structure, Tertiary
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Sequence Alignment
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Sequence Homology, Amino Acid
Substances
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Bacterial Proteins
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Bone Morphogenetic Proteins
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Glycoproteins
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Intercellular Signaling Peptides and Proteins
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chordin