Geraniol, the putative anthelmintic principle of Cymbopogon martinii

Phytother Res. 2003 Sep;17(8):957. doi: 10.1002/ptr.1267.

Abstract

The essential oil of Cymbopogon martinii (palmrosa) and one of its main constituents geraniol were tested for anthelmintic activity (in vitro) employing the nematode, Caenorhabditis elegans. Both the substances showed potent anthelmintic activity. The ED50 of geraniol was found to be 66.7 mcg/mL, suggesting geraniol as the putative anthelmintic principle of palmrosa oil.

MeSH terms

  • Acyclic Monoterpenes
  • Animals
  • Anthelmintics / administration & dosage
  • Anthelmintics / pharmacology*
  • Anthelmintics / therapeutic use
  • Benzaldehydes / pharmacology
  • Caenorhabditis elegans / drug effects*
  • Cymbopogon*
  • Humans
  • Levamisole / pharmacology
  • Parasitic Sensitivity Tests
  • Phytotherapy*
  • Plant Oils / administration & dosage
  • Plant Oils / pharmacology*
  • Plant Oils / therapeutic use
  • Terpenes / administration & dosage
  • Terpenes / pharmacology*
  • Terpenes / therapeutic use

Substances

  • Acyclic Monoterpenes
  • Anthelmintics
  • Benzaldehydes
  • Plant Oils
  • Terpenes
  • Levamisole
  • 4-anisaldehyde
  • geraniol