Growth hormone and the kidney: a case presentation and review of the literature

J Am Soc Nephrol. 1992 Aug;3(2):157-61. doi: 10.1681/ASN.V32157.

Abstract

Hypersomatotropism is accompanied by a significant increase in GFR and RPF. A case of a patient with acromegaly and supranormal renal function as measured by inulin and p-aminohippurate clearances is reported. The literature regarding the effects of growth hormone on renal function is reviewed, and the potential mechanisms of action and therapeutic implications of these effects are discussed.

Publication types

  • Case Reports
  • Historical Article
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Acromegaly / history
  • Acromegaly / metabolism
  • Adult
  • Body Water / metabolism
  • Extracellular Space / metabolism
  • Glomerular Filtration Rate
  • Growth Hormone / metabolism
  • Growth Hormone / pharmacology*
  • History, 20th Century
  • Humans
  • Insulin-Like Growth Factor I / pharmacology
  • Kidney / metabolism*
  • Kidney / pathology
  • Kidney Diseases / metabolism*
  • Kidney Diseases / pathology
  • Male

Substances

  • Insulin-Like Growth Factor I
  • Growth Hormone