Abstract
A case of congenital chloride diarrhea was diagnosed after delivery in a patient whose antenatal course was notable for massively dilated small and large bowel and persistent, severe hydramnios refractory to therapy. The pathophysiologic mechanism is a dysfunctional chloride-bicarbonate exchange in the brush border of the ileum. Antenatal presentation, prenatal diagnosis, and a review of the current literature are discussed.
MeSH terms
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Adult
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Amniocentesis
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Chlorides / physiology
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Diarrhea, Infantile / congenital*
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Diarrhea, Infantile / diagnostic imaging
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Diarrhea, Infantile / physiopathology
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Diarrhea, Infantile / therapy
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Female
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Humans
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Infant, Newborn
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Intestinal Obstruction / diagnostic imaging
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Intestinal Obstruction / etiology*
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Intestinal Obstruction / surgery
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Polyhydramnios / complications*
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Polyhydramnios / therapy
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Pregnancy
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Ultrasonography, Prenatal