Using the Konan-Keeler specular microscope, panoramic specular microscopy covering almost one quadrant of the anterior capsule was performed. Regional changes in the retained lens epithelial cells were recorded and compared simultaneously. The nearer the rim of the anterior capsular opening, the greater the decrease of cell density, increase of average cell size, and variety of cell size. The results indicate that the first postoperative changes in lens epithelial cells following phacoemulsification with subsequent capsular bag intraocular lens implantation occur in the area close to the anterior capsular opening, with subsequent changes in peripheral areas.