Purpose: To determine the clinical differences between three-piece (3P) and single-piece (SP) truncated hydrophobic acrylic intraocular lenses (IOL).
Design: Retrospective cohort clinical study.
Methods: The setting was an academic clinical practice. The patient population consisted of subjects without confounding comorbidity that could effect central vision with at least 1-year follow-up after uncomplicated surgical placement of 3P or SP IOLs in the capsular bag and at least 20/25 best-corrected postoperative vision documented. Observation procedures were as follows: logarithm of the minimal angle of resolution (LogMAR) visual acuity (uncorrected and best corrected), digital retroillumination photographs to ascertain posterior capsular opacification (PCO), anterior capsular opacification (ACO), IOL centration, and refractive stability by comparing this refraction with the early postoperative refraction. Patients completed a dysphotopsia questionnaire. Main outcome measures were as follows: LogMAR visual acuity (uncorrected and best corrected), PCO, ACO, IOL centration, refractive stability, and dysphotopsia outcomes comparing 3P and SP.
Results: Seventy-five patients were enrolled (36 3P and 39 SP). Corrected and uncorrected visual acuity, refractive stability, and IOL centration were similar. Single piece truncated hydrophobic acrylic intraocular lenses had more PCO (P =.013), less ACO (P =.001), less central flash looking at a peripheral light (P =.044), and less unwanted images to the side of a light source (P =.025) .
Conclusions: Although similar in centration and refractive stability, SP has more PCO, less ACO, and less dysphotopsia than 3P.