Combined phacoemulsification, intraocular lens implantation and trabeculectomy for chronic angle closure glaucoma

Int Ophthalmol. 2001;24(5):283-9. doi: 10.1023/a:1025478923950.

Abstract

Purpose: To investigate the results of combined phacoemulsification, intraocular lens implantation and trabeculectomy in Asian patients with chronic angle closure glaucoma (CACG).

Methods: This was a retrospective non-comparative case series of 55 consecutive patients (57 eyes) who underwent phacoemulsification, posterior chamber intraocular lens implantation and trabeculectomy for CACG at the Singapore National Eye Centre between 1997-1998. The surgical outcome was assessed in terms of intraocular pressure (IOP), the incidence of complications and the visual acuity at last follow-up. Success was defined as final IOP < or = 21 mmHg without medication and qualified success as final IOP < or = 21 mmHg with medication. Patients with final IOP > 21 mmHg who required further glaucoma surgery, lost light perception or became pthisical, were classified as failures. The eyes were further categorized into two groups according to whether single-site or separate-site surgery was performed. The outcome was also compared among eyes in which per-operative antimetabolites were applied to the trabeculectomy site and those without antimetabolites.

Results: The mean follow up was 22.0 +/- 5.6 months (mean +/- SD). Success was achieved in 46 (81%) eyes, qualified success in 10 (17%) eyes, and failure in 1 (2%) eye. In terms of IOP outcome, the success rate was similar in the two surgical groups (single-site or separate-site). There was no significant difference in IOP outcome among eyes in which per-operative antimetabolites were used and eyes with no per-operative antimetabolites use. Forty-one eyes (72%) had 6/12 or better vision. There were no cases of intraoperative complications and the incidence of postoperative complications was low.

Conclusions: Combined phacoemulsification, intraocular lens implantation and trabeculectomy is associated with good intraocular pressure control and visual outcome in patients with CACG.

MeSH terms

  • Aged
  • Asian People
  • Chronic Disease
  • Female
  • Glaucoma, Angle-Closure / ethnology
  • Glaucoma, Angle-Closure / physiopathology
  • Glaucoma, Angle-Closure / surgery*
  • Humans
  • Intraocular Pressure
  • Lens Implantation, Intraocular* / adverse effects
  • Male
  • Middle Aged
  • Phacoemulsification* / adverse effects
  • Retrospective Studies
  • Trabeculectomy* / adverse effects
  • Treatment Outcome
  • Visual Acuity