Biorecognition-modulated ion fluxes through functionalized gold nanotubules as a novel label-free biosensing approach

Chem Commun (Camb). 2003 Oct 21:(20):2560-1. doi: 10.1039/b307393a.

Abstract

A novel biosensing principle is presented, based on the potentiometric monitoring of an indicator ion such as Ca2+, whose zero-current flux through chemically modified nanochannels is altered by biorecognition events.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Avidin / chemistry
  • Biosensing Techniques / instrumentation*
  • Biosensing Techniques / methods*
  • Calcium / analysis*
  • Calcium / chemistry
  • Gold / chemistry*
  • Nanotubes / chemistry*
  • Potentiometry
  • Time Factors

Substances

  • Avidin
  • Gold
  • Calcium