Determinants of quality of life in first-episode psychosis

Acta Psychiatr Scand. 2004 Jan;109(1):46-54. doi: 10.1046/j.0001-690x.2003.00221.x.

Abstract

Objective: To assess patient and/or illness characteristics associated with aspects of quality of life (QOL) in first-episode psychosis (FEP).

Method: Patient characteristics, symptom ratings and Wisconsin QOL scale (client version) were assessed. Data were analysed with correlation coefficients and a hierarchical regression analysis.

Results: Patients presented with varying levels of QOL on different domains. The level of 'general satisfaction' was related to age of onset and social premorbid adjustment; 'weighted index of QOL' to social premorbid adjustment and inversely to educational premorbid adjustment; 'social relations' inversely to duration of untreated psychosis (DUP), length of prodrome and negative symptoms; 'psychological well-being' inversely to depression and educational premorbid adjustment; 'activities of daily living' to social premorbid adjustment and inversely to negative symptoms; and 'outlook on symptoms' to level of depression.

Conclusion: Domains of self-rated QOL in FEP patients are differentially associated with malleable and non-malleable aspects of patient and illness characteristics.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Diagnostic and Statistical Manual of Mental Disorders
  • Female
  • Hospitalization
  • Humans
  • Male
  • Psychotic Disorders / diagnosis
  • Psychotic Disorders / psychology*
  • Psychotic Disorders / rehabilitation
  • Quality of Life*
  • Regression Analysis
  • Social Adjustment
  • Surveys and Questionnaires*