Effective weekly docetaxel for recurrent ovarian cancer: A case report

Int J Gynecol Cancer. 2003 Sep-Oct;13(5):683-6. doi: 10.1046/j.1525-1438.2003.13042.x.

Abstract

We experienced a case of recurrent ovarian cancer that responded to weekly docetaxel. The patient had stage IIIC ovarian cancer (poorly differentiated serous adenocarcinoma). After initial remission was achieved by chemotherapy with paclitaxel and carboplatin plus cytoreductive surgery, the disease recurred and irinotecan therapy achieved temporary remission. During maintenance therapy with oral etoposide, the disease recurred again. We then tried five courses of weekly docetaxel therapy and it successfully controlled the disease. The progression-free survival time on weekly docetaxel treatment is now 7 months and the toxicity was extremely low. This patient demonstrates the effectiveness of weekly docetaxel as salvage chemotherapy for recurrent ovarian cancer.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents, Phytogenic / administration & dosage*
  • Cystadenocarcinoma, Serous / diagnostic imaging
  • Cystadenocarcinoma, Serous / pathology
  • Cystadenocarcinoma, Serous / therapy*
  • Docetaxel
  • Drug Administration Schedule
  • Female
  • Humans
  • Middle Aged
  • Neoplasm Recurrence, Local / diagnostic imaging
  • Neoplasm Recurrence, Local / drug therapy*
  • Neoplasm Recurrence, Local / pathology
  • Neoplasm Staging
  • Ovarian Neoplasms / diagnostic imaging
  • Ovarian Neoplasms / pathology
  • Ovarian Neoplasms / therapy*
  • Palliative Care
  • Radiography
  • Taxoids / administration & dosage*

Substances

  • Antineoplastic Agents, Phytogenic
  • Taxoids
  • Docetaxel