A deep-rough mutant of Campylobacter jejuni 81-176 is noninvasive for intestinal epithelial cells

Infect Immun. 2004 Apr;72(4):2452-5. doi: 10.1128/IAI.72.4.2452-2455.2004.

Abstract

A waaF mutant of Campylobacter jejuni 81-176 showed decreased invasion of INT407 cells in vitro and increased sensitivity to some antibiotics compared to what was seen with the wild-type strain.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism
  • Campylobacter jejuni / enzymology
  • Campylobacter jejuni / genetics
  • Campylobacter jejuni / growth & development*
  • Campylobacter jejuni / pathogenicity*
  • Cell Line
  • Epithelial Cells / microbiology*
  • Glycosyltransferases / genetics
  • Glycosyltransferases / metabolism
  • Humans
  • Intestines / cytology
  • Intestines / microbiology*
  • Lipopolysaccharides / chemistry
  • Lipopolysaccharides / metabolism
  • Molecular Sequence Data
  • Mutation*

Substances

  • Bacterial Proteins
  • Lipopolysaccharides
  • lipid-linked oligosaccharides
  • Glycosyltransferases
  • heptosyltransferase

Associated data

  • GENBANK/AY423899