Abstract
We report the detection and characterization of the first vancomycin-resistant VanB-type Enterococcus faecium to be isolated in a Spanish hospital. Sequence analysis of the vanB gene showed that this isolate belonged to subtype vanB2. Moreover, PCR amplification analysis indicated that the vanB gene cluster was linked to a Tn5382-like transposon.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Aged
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Anti-Bacterial Agents / pharmacology
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Base Sequence
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DNA Transposable Elements / genetics
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DNA Transposable Elements / physiology
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DNA, Bacterial / chemistry
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DNA, Bacterial / isolation & purification
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Drug Resistance, Bacterial
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Enterococcus faecium / drug effects*
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Enterococcus faecium / genetics*
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Enterococcus faecium / growth & development
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Enterococcus faecium / isolation & purification
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Genes, Bacterial / genetics
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Genes, Bacterial / physiology
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Gram-Positive Bacterial Infections / microbiology*
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Hospitals
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Humans
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Male
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Molecular Sequence Data
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Pressure Ulcer / microbiology
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Sequence Alignment
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Sequence Analysis, DNA
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Sequence Homology
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Spain
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Vancomycin / pharmacology*
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Vancomycin Resistance*
Substances
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Anti-Bacterial Agents
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DNA Transposable Elements
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DNA, Bacterial
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Vancomycin