Gemcitabine and vinorelbine as a salvage regimen for relapse in Hodgkin lymphoma after autologous hematopoietic stem cell transplantation

Pediatr Hematol Oncol. 2004 Mar;21(2):107-13. doi: 10.1080/08880010490272975.

Abstract

The authors describe two consecutive pediatric patients with relapsed Hodgkin lymphoma after autologous hematopoietic stem cell transplantation who had objective responses with a novel combination of gemcitabine and vinorelbine. This novel and promising combination needs to be studied in a larger number of relapsed Hodgkin disease patients.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Combined Modality Therapy
  • Deoxycytidine / analogs & derivatives*
  • Deoxycytidine / therapeutic use*
  • Female
  • Gemcitabine
  • Hematopoietic Stem Cell Transplantation
  • Hodgkin Disease / drug therapy*
  • Hodgkin Disease / therapy
  • Humans
  • Salvage Therapy / methods*
  • Transplantation, Autologous
  • Treatment Outcome
  • Vinblastine / analogs & derivatives*
  • Vinblastine / therapeutic use*
  • Vinorelbine

Substances

  • Deoxycytidine
  • Vinblastine
  • Vinorelbine
  • Gemcitabine