Purpose: To report a series of cases with asymmetric keratoconus attributed to eye rubbing, discuss its pathogenesis, and review the literature.
Methods: Case reports and literature review.
Results: A careful history obtained from 5 patients with asymmetric keratoconus revealed habitual eye rubbing of the more severely affected eye.
Conclusions: Trauma, such as occurs with habitual eye rubbing, plays a role in the pathogenesis of keratoconus.