In vitro inhibition of human immunodeficiency virus type-1 (HIV-1) reverse transcriptase by gold(III) porphyrins

Chembiochem. 2004 Sep 6;5(9):1293-8. doi: 10.1002/cbic.200300773.

Authors

Raymond Wai-Yin Sun¹, Wing-Yiu Yu, Hongzhe Sun, Chi-Ming Che

Affiliation

¹ Open Laboratory of Chemical Biology, Institute of Molecular Technology for Drug Discovery and Synthesis, Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China.

PMID: 15368585
DOI: 10.1002/cbic.200300773

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cell Survival / drug effects
Enzyme-Linked Immunosorbent Assay
Gold*
HIV Reverse Transcriptase / antagonists & inhibitors*
Humans
In Vitro Techniques
Indicators and Reagents
Ligands
Magnetic Resonance Spectroscopy
Peptides / chemical synthesis
Peptides / pharmacology
Porphyrins / chemical synthesis
Porphyrins / pharmacology*
Reverse Transcriptase Inhibitors / pharmacology*
Solvents
Spectrophotometry, Ultraviolet
T-Lymphocytes / drug effects
T-Lymphocytes / metabolism

Substances

Indicators and Reagents
Ligands
Peptides
Porphyrins
Reverse Transcriptase Inhibitors
Solvents
Gold
HIV Reverse Transcriptase