Cardiovascular risk beyond LDL-C levels. Other lipids are performers in cholesterol story

Postgrad Med. 2004 Sep;116(3):11-5. doi: 10.3810/pgm.2004.09.1584.

Abstract

High levels of low-density lipoprotein cholesterol (LDL-C) are an obvious culprit in coronary artery disease (CAD). However, the search for lipid factors that influence cardiovascular health does not end there. In this article, Dr Nash presents the various lipid factors involved, for better or worse, in CAD. He emphasizes that although studies have expanded the understanding of this disease, the knowledge needs to be put to use more consistently in clinical practice in order to provide optimal patient care.

Publication types

  • Review

MeSH terms

  • Animals
  • Apolipoprotein A-I / metabolism
  • Apolipoprotein A-I / therapeutic use
  • Arteriosclerosis / drug therapy
  • Cholesterol, HDL / metabolism
  • Cholesterol, LDL / metabolism
  • Coronary Artery Disease / etiology*
  • Coronary Artery Disease / metabolism*
  • Coronary Artery Disease / prevention & control
  • Humans
  • Hyperlipidemias / complications*
  • Hyperlipidemias / metabolism*
  • Hyperlipidemias / prevention & control
  • Hypertriglyceridemia / complications
  • Hypertriglyceridemia / metabolism
  • Hypertriglyceridemia / prevention & control
  • Life Style
  • Obesity / complications
  • Obesity / metabolism
  • Obesity / prevention & control
  • Phosphatidylcholines / therapeutic use
  • Risk Factors
  • Treatment Outcome

Substances

  • Apolipoprotein A-I
  • Cholesterol, HDL
  • Cholesterol, LDL
  • ETC216
  • Phosphatidylcholines
  • apolipoprotein A-I Milano