[Chromosomal localization of the KMP-11 genes in the KP1(+) and KP1(-) strains of Trypanosoma rangeli]

Claudia Urueña; Paola Santander; Hugo Díez; Marleny Montilla; Ignacio Zarante; María del Carmen Thomas; Manuel Carlos López; Concepción Puerta

[Chromosomal localization of the KMP-11 genes in the KP1(+) and KP1(-) strains of Trypanosoma rangeli]

Biomedica. 2004 Jun;24(2):200-3.

[Article in Spanish]

Authors

Claudia Urueña¹, Paola Santander, Hugo Díez, Marleny Montilla, Ignacio Zarante, María del Carmen Thomas, Manuel Carlos López, Concepción Puerta

Affiliation

¹ Laboratorio de Parasitología Molecular, Departamento de Microbiología, Facultad de Ciencias, Pontifica Universidad Javeriana, Bogotá, DC, Colombia.

PMID: 15495600

Abstract

Genes encoding for the KMP-11 protein were localized on the chromosomes of Trypanosoma rangeli. These genes were located in two chromosomes of 3,100 and 3,400 kb in the KP1(-) strain whereas in the KP1(+) H14 and Choachí strains, the genes are located in a chromosome of 1,600 kb. The Choachí strain presents an additional band of 1,400 kb. In the Shubacbarina and Munanta strains of Trypanosoma cruzi, the KMP-11 genes are located on a chromosomal band of 1,490 kb. Therefore, the chromosomal localization of the KMP-11 genes presents a potential tool to differentiate among these parasites.

Publication types

English Abstract
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Chromosomes, Bacterial / genetics
Membrane Glycoproteins / genetics*
Protozoan Proteins / genetics*
Trypanosoma / genetics*

Substances

Membrane Glycoproteins
Protozoan Proteins
kinetoplastid membrane protein 11, Leishmania donovani