Optimal cytoreduction after combined resection and radiofrequency ablation of hepatic metastases from recurrent malignant ovarian tumors

Gynecol Oncol. 2005 Apr;97(1):266-70. doi: 10.1016/j.ygyno.2004.12.038.

Abstract

Background: The role of radiofrequency ablation (RFA) in the treatment of hepatic metastases from recurrent ovarian tumors is undefined.

Case: Three patients with hepatic lesions from recurrent ovarian cancers underwent a combined partial hepatectomy with radiofrequency ablation (RFA) to achieve optimal tumor cytoreduction. Follow-up radiological studies as well as serial tumor markers are consistent with disease-free survival after 39, 13, and 9 months.

Conclusion: These results demonstrate the feasibility and safety of RFA for metastatic ovarian lesions to the liver in patients previously deemed as poor or non-surgical candidates, and suggest the potential for improvement in survival over unresected patients or in patients resected with residual disease.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Catheter Ablation
  • Female
  • Hepatectomy / methods
  • Humans
  • Liver Neoplasms / secondary*
  • Liver Neoplasms / surgery*
  • Middle Aged
  • Neoplasm Recurrence, Local / pathology*
  • Neoplasm Recurrence, Local / surgery*
  • Ovarian Neoplasms / pathology*
  • Ovarian Neoplasms / surgery*