Is there any evidence for an association between ankylosing spondylitis and Borrelia burgdorferi infection?

I Blaauw; L Nohlmans; A Peeters; B Dijkmans; S van der Linden

Is there any evidence for an association between ankylosing spondylitis and Borrelia burgdorferi infection?

J Rheumatol. 1992 Apr;19(4):579-81.

Authors

I Blaauw¹, L Nohlmans, A Peeters, B Dijkmans, S van der Linden

Affiliation

¹ Department of Internal Medicine, University Hospital of Maastricht, The Netherlands.

PMID: 1593580

Abstract

The suggested relationship between Borrelia burgdorferi and seronegative spondyloarthropathies has been studied in 125 patients with ankylosing spondylitis (AS). IgG antibodies to Borrelia burgdorferi were present in 11 of 125 patients (8.8%) and in 25 of 125 controls (20%). No patient had clinical Lyme borreliosis. HLA-B27 status was known for 82 patients with AS. There was no difference between B27+ and B27 patients. This study provides no evidence that Borrelia burgdorferi is associated with AS.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Antibodies, Bacterial / analysis
Borrelia burgdorferi Group / immunology
HLA-B27 Antigen / analysis
Humans
Immunoglobulin G / analysis
Lyme Disease* / diagnosis
Lyme Disease* / immunology
Reference Values
Serologic Tests
Spondylitis, Ankylosing / microbiology*

Substances

Antibodies, Bacterial
HLA-B27 Antigen
Immunoglobulin G