Abstract
Plant sterol and stanol esters each have similar additive effects in lowering low-density lipoprotein cholesterol when combined with statins. They differ in that plasma plant sterols increase when plant sterol esters are used for this purpose, especially in patients with familial hypercholesterolemia, but decrease when plant stanol esters are used.
MeSH terms
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Cholesterol, LDL / metabolism
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Drug Interactions
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Drug Therapy, Combination
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Humans
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Hyperlipoproteinemia Type II / drug therapy*
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Phytosterols / pharmacology*
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Phytosterols / therapeutic use*
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Phytotherapy*
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Randomized Controlled Trials as Topic
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Sitosterols / pharmacology*
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Sitosterols / therapeutic use*
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Treatment Outcome
Substances
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Cholesterol, LDL
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Phytosterols
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Sitosterols
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plant stanol ester