St John's wort-associated drug interactions: short-term inhibition and long-term induction?

Clin Pharmacol Ther. 2005 Jul;78(1):19-24. doi: 10.1016/j.clpt.2005.04.002.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.
  • Review
  • Comment

MeSH terms

  • Cytochrome P-450 Enzyme Inhibitors
  • Cytochrome P-450 Enzyme System / biosynthesis
  • Cytochrome P-450 Enzyme System / pharmacology*
  • Drug Interactions*
  • Flowers / chemistry
  • Flowers / metabolism
  • Hypericum / chemistry
  • Hypericum / metabolism
  • Hypericum / physiology*
  • Multidrug Resistance-Associated Proteins / antagonists & inhibitors*
  • Multidrug Resistance-Associated Proteins / biosynthesis*
  • Multidrug Resistance-Associated Proteins / drug effects
  • Plant Extracts / economics
  • Plant Extracts / metabolism
  • Plant Extracts / therapeutic use
  • Time Factors

Substances

  • Cytochrome P-450 Enzyme Inhibitors
  • Multidrug Resistance-Associated Proteins
  • Plant Extracts
  • Cytochrome P-450 Enzyme System
  • multidrug resistance-associated protein 1