In order to assess changes from 1986 to 1989 in knowledge, beliefs, and risk factors for AIDS, the responses of inner-city adolescent girls were compared. Although 63% of the 1989 cohort received AIDS education in school, the base knowledge of the two cohorts was not markedly different. Between 1986 and 1989, the number of sexual partners increased for adolescents of all ethnic groups, yet concerns about AIDS showed a decline. Those adolescents who had the highest number of sexual partners were also those who had the most knowledge and most concerns about AIDS. Implications for preventive education focus on ethnic diversity and gaps between adolescent knowledge and behavior.