[Status of extracellular matrix and adhesion markers in urothelial cancer of the urinary bladder]

Arkh Patol. 2005 May-Jun;67(3):11-4.
[Article in Russian]

Abstract

39 cases of transitory cell (15 cases of well differentiated, 12-moderately and 12- poorly differentiated) urothelial bladder carcinoma were studied immunohistochemically. Expression of adhesion molecules, collagen, laminin and tenascsin was investigated. Their role in a decrease of a differentiation degree of urothelial carcinoma was revealed. The possibility of the above markers use for individual prognosis is demonstrated.

Publication types

  • English Abstract

MeSH terms

  • Biomarkers, Tumor / analysis*
  • Carcinoma / diagnosis*
  • Carcinoma / immunology
  • Cell Adhesion
  • Cell Adhesion Molecules / analysis*
  • Extracellular Matrix / immunology
  • Extracellular Matrix / pathology
  • Extracellular Matrix Proteins / analysis*
  • Humans
  • Prognosis
  • Tissue Adhesions / immunology
  • Urinary Bladder Neoplasms / diagnosis*
  • Urinary Bladder Neoplasms / immunology
  • Urothelium / immunology
  • Urothelium / pathology

Substances

  • Biomarkers, Tumor
  • Cell Adhesion Molecules
  • Extracellular Matrix Proteins