Abstract
We describe an 18-year-old man with a 7-year history of severe major aphthous stomatitis refractory to multiple standard therapies who responded completely to therapy with adalimumab, a fully humanized monoclonal antibody against tumor necrosis factor alpha (TNF-alpha).
MeSH terms
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Adalimumab
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Adolescent
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Antibodies, Monoclonal / therapeutic use*
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Antibodies, Monoclonal, Humanized
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Humans
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Male
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Recurrence
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Stomatitis, Aphthous / drug therapy*
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Tumor Necrosis Factor-alpha / immunology
Substances
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Antibodies, Monoclonal
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Antibodies, Monoclonal, Humanized
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Tumor Necrosis Factor-alpha
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Adalimumab