Self-assembly of symmetric finite-size DNA nanoarrays

J Am Chem Soc. 2005 Dec 14;127(49):17140-1. doi: 10.1021/ja055614o.

Abstract

We report a novel and cost-effective strategy to self-assemble finite-size DNA nanoarrays. This strategy takes advantage of the geometric symmetry of the DNA nanostructures. In general, to construct a 2D array with a total of N tiles containing Cm symmetry, where m = 2, 3, 4, or 6, the number of unique tiles the fixed-size array requires is N/m, if N/m is an integral number, or Int(N/m) + 1, if N/m is an nonintegral number. We herein demonstrate two examples of fixed-size arrays with C2 and C4-fold symmetry.dagger

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • DNA / chemistry*
  • Nanostructures / chemistry*
  • Nanostructures / economics

Substances

  • DNA