Abstract
The effect of quetiapine (an atypical antipsychotic with minimal extrapyramidal side effects) on motor as well as behavioral symptoms was studied in five consecutive patients with Huntington's disease in a long-term facility. Improvement of behavioral symptoms (i.e., psychotic symptoms, agitation, irritability, and insomnia) without worsening of motor functioning were noted.
MeSH terms
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Adult
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Antipsychotic Agents / adverse effects
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Antipsychotic Agents / therapeutic use*
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Dibenzothiazepines / adverse effects
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Dibenzothiazepines / therapeutic use*
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Female
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Follow-Up Studies
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Humans
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Huntington Disease / complications*
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Huntington Disease / psychology
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Long-Term Care / methods
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Long-Term Care / psychology
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Male
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Mental Disorders / drug therapy*
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Mental Disorders / etiology*
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Mental Disorders / psychology
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Psychomotor Agitation / drug therapy
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Psychomotor Agitation / etiology
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Psychomotor Agitation / psychology
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Psychotic Disorders / drug therapy
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Psychotic Disorders / etiology
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Psychotic Disorders / psychology
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Quetiapine Fumarate
Substances
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Antipsychotic Agents
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Dibenzothiazepines
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Quetiapine Fumarate