Acute myelogenous leukemia in a patient with Li-Fraumeni syndrome treated with valproic acid, theophyllamine and all-trans retinoic acid: a case report

Leukemia. 2006 Apr;20(4):734-6. doi: 10.1038/sj.leu.2404117.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aminophylline / therapeutic use*
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • DNA-Binding Proteins / metabolism
  • Drug Therapy, Combination
  • Female
  • Genes, Tumor Suppressor
  • Humans
  • Leukemia, Myeloid, Acute / complications*
  • Leukemia, Myeloid, Acute / drug therapy*
  • Leukemia, Myeloid, Acute / genetics
  • Li-Fraumeni Syndrome / complications*
  • Li-Fraumeni Syndrome / genetics
  • Li-Fraumeni Syndrome / therapy*
  • Middle Aged
  • Mutation
  • Nuclear Proteins / metabolism
  • Treatment Outcome
  • Tretinoin / therapeutic use*
  • Tumor Protein p73
  • Tumor Suppressor Protein p53 / genetics
  • Tumor Suppressor Proteins
  • Valproic Acid / therapeutic use*

Substances

  • DNA-Binding Proteins
  • Nuclear Proteins
  • Tumor Protein p73
  • Tumor Suppressor Protein p53
  • Tumor Suppressor Proteins
  • Aminophylline
  • Tretinoin
  • Valproic Acid