Abstract
Melatonin (N-acetyl-5-methoxytryptamine) is a hormone produced by the pineal gland in the brain in response to darkness. Melatonin is made available when tryptophan is converted to serotonin and then enzymatically converted to melatonin in the pineal gland. Serum levels are low during the day, with peak levels occurring from 2-4 am.
MeSH terms
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Adjuvants, Immunologic / physiology
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Adjuvants, Immunologic / therapeutic use*
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Antioxidants / physiology
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Antioxidants / therapeutic use*
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Circadian Rhythm / drug effects
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Complementary Therapies / organization & administration*
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Contraindications
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Drug Interactions
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Evidence-Based Medicine / organization & administration*
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Humans
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Melatonin / physiology
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Melatonin / therapeutic use*
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Neoplasms / drug therapy*
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Patient Education as Topic
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Patient Selection
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Safety
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Sleep Initiation and Maintenance Disorders / drug therapy
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Travel
Substances
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Adjuvants, Immunologic
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Antioxidants
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Melatonin