Direct C-allylation of aryl-alkyl/glycosyl carbinols: facile synthesis of C-linked carbo-beta2-/gamma2-/delta2-amino acids

J Org Chem. 2006 May 12;71(10):3967-9. doi: 10.1021/jo052418r.

Abstract

A facile ZrCl4-catalyzed direct allylation of the p-methoxyphenyl-alkyl/glycosyl carbinols at room temperature, and the conversion of the derived aryl-glycosyl-alkenes into hitherto unknown C-linked carbo-beta2-/gamma2-/delta2-amino acids is reported.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acids / chemical synthesis*
  • Methanol / chemistry*
  • Models, Molecular
  • Molecular Structure

Substances

  • Amino Acids
  • Methanol